🧬 Type IV Hypersensitivity: CD8+ T-Cell–Mediated Cytotoxicity
Learn Type IV hypersensitivity for the MCAT, including CD8+ T-cell cytotoxicity, MHC I recognition, perforin, granzymes, Fas–FasL, and apoptosis.
Adaptive Immune System: MCAT Breakdown of CD8+ Cytotoxic T Cells
CD8+ T cells are a subset of T lymphocytes that recognize and eliminate infected or cancerous cells. These immune cells play a crucial role in adaptive immunity by binding to major histocompatibility complex class I (MHC I) molecules, which present antigens from intracellular pathogens.