Guillain-Barré Syndrome – A High-Yield Neurology Topic You Can’t Miss

Sudden ascending weakness? Areflexia? Recent diarrhea?
If you see this in a USMLE vignette, there’s only one diagnosis that should flash in your brain—Guillain-Barré Syndrome (GBS). This autoimmune demyelinating polyneuropathy is a Step 1 and Step 2 favorite, often appearing in both diagnosis and management questions.