💊 Digoxin NCLEX Guide: Use, Toxicity Signs, and Nursing Care
Digoxin (Lanoxin) is a cardiac glycoside used to treat heart failure and atrial fibrillation.
Because of its narrow therapeutic range and life-threatening toxicity, it’s a high-yield drug for NCLEX pharmacology questions.
This blog features a signature KOTC visual and a breakdown of dosing, lab monitoring, and warning signs.
📊 Digoxin NCLEX Quick Reference Table
| Use | Heart failure, atrial fibrillation |
|---|---|
| Therapeutic Range | 0.5–2.0 ng/mL |
| Hold If HR < | 60 bpm (adult), 90 bpm (infant) |
| Route | PO or IV |
| Excretion | Renal – monitor kidney function |
| Toxicity Signs | Nausea, vomiting, bradycardia, halos, blurred/yellow vision |
| Antidote | Digibind (Digoxin immune Fab) |
| Labs to Monitor | Digoxin level, potassium, BUN/Cr |
🧠 NCLEX Tip: Hypokalemia Increases Toxicity Risk
Low potassium = higher digoxin sensitivity
Be extra cautious in patients on diuretics (furosemide)
🩺 Nursing Responsibilities with Digoxin
Check apical HR for 1 full minute before admin
Hold and notify if HR <60 bpm (or <90 bpm in infants)
Monitor digoxin levels regularly
Watch for early signs of toxicity
Educate patient to report vision changes or GI upset
Monitor electrolytes, especially potassium
💡 Mnemonic: “DIG IT”
D – Dig level 0.5–2
I – Increases contractility
G – GI and vision = early signs of toxicity
I – Interacts with potassium
T – Take apical pulse before giving
📲 Study Pharm Like a Pro with King of the Curve
💊 Pharmacology flashcards by system
⚠️ Toxicity alert simulations
🧪 Digoxin & cardiac drug practice sets
Explore at kingofthecurve.org/studyscience
🏁 Final Thoughts
Digoxin is easy to remember if you know where it goes wrong.
Think: slow heart, yellow vision, and low potassium danger.
Frequently Asked Questions (FAQs)
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